Dr. Shen, Chih-Lung
E-mail:winpower0105@gmail.com
Ext15913
Tzu Chi University, Taiwan. Ph.D.  

Expertise

(Tumor Virology) Molecular virology) (Molecular biology)

          (Gene expression and regulation)

Interest

  1. Efficient culture of human B cells for use as APCs
  2. Platelet function tests in clinical research

 

Publication (in five years)

1.

Chen, Y. L., C. D. Liu, C. P. Cheng, B. Zhao, H. J. Hsu, C. L. Shen, S. J. Chiu, E. Kieff and C. W. Peng (2014). "Nucleolin is important for Epstein-Barr virus nuclear antigen 1-mediated episome binding, maintenance, and transcription." Proc Natl Acad Sci U S A 111(1): 243-248. (SCI, IF: 9.6)

2.

Harter, M. R., C. D. Liu, C. L. Shen, E. Gonzalez-Hurtado, Z. M. Zhang, M. Xu, E. Martinez, C. W. Peng and J. Song (2016). "BS69/ZMYND11 C-Terminal Domains Bind and Inhibit EBNA2." PLoS Pathog 12(2): e1005414. (SCI, IF:6.5)

3.

Shen, C. L., C. D. Liu, R. I. You, Y. H. Ching, J. Liang, L. Ke, Y. L. Chen, H. C. Chen, H. J. Hsu, J. W. Liou, E. Kieff and C. W. Peng (2016). "Ribosome Protein L4 is essential for Epstein-Barr Virus Nuclear Antigen 1 function." Proc Natl Acad Sci U S A 113(8): 2229-2234. (SCI, IF: 9.6)

4.

Shen, C. L., W. H. Huang, H. J. Hsu, J. H. Yang and C. W. Peng (2019). "GAP31 from an ancient medicinal plant exhibits anti-viral activity through targeting to Epstein-Barr virus nuclear antigen 1." Antiviral Res 164: 123-130. (SCI, IF: 4.1)

                                               

 

  Dr. Hsieh, Yi-Jen
E-mail: hij@mail.tcu.edu.tw
Ext03-856501#2674(Tzu Chi University)
National Dong Hwa University Ph.D.

Expertise

(Analysis of Chinese Herbal Medicines and Bioanalysis) 

(Signal transduction)

Interest

  1. (Analysis of Chinese Herbal Medicines and Bioanalysis)
  2. (Molecular Mechanisms and New Anti-Cancer Drug Development)

Publication (in five years)

1.

Tzu-Chia Ting, Meng-Ya Chang,Tzu-Yen Hsu, Wen-Pin Wang,Yi-Jen Hsieh and   Chih-Jui Chang, (2018) “Vanadocene dichloride inhibits cell proliferation by targeting Aurora B” Metallomics, 10(8), 1099-1106. (SCI, IF: 3.57)

2.

Yi-Jen Hsieh,Hsuan-Shun Huang, Yann-Lii Leu, Kou-Cheng Peng, Chih-Jui Chang and Meng-Ya Chang, (2015) “Anticancer activity of Kalanchoe tubiflora extract against human lung cancer cells in vitro and in vivo, Environmental Toxicology, 31(11), 1663-1673. (SCI, IF: 2.87).

                                               

 

National Dong Hwa University Ph.D.

  Dr. Chao, Tung-Hui
E-mail:t9990224@gmail.com
Ext15927
Tzu Chi University, Taiwan. Ph.D.  

Expertise

(Tumor Biology) (Gene transcription regulation)

(Reactive Oxygen Species analysis)

Interest

  1. (Tumor Biology)
  2. (Gene transcription regulation)

  3. (Reactive Oxygen Species analysis)

  4. (The mechanism of osteoporosis)

Publication (in five years)

1.

Inducible nitric oxide synthase mediates MG132 lethality in leukemic cells    

throughmitochondrial depolarization. Chao TH, Chang MY, Su SJ, Su SH., Free Radic Biol Med. 2014 Sep;74:175-87.

2.

Progesterone Prevents High-Grade Serous Ovarian Cancer by Inducing Necroptosis of p53-Defective Fallopian Tube Epithelial Cells.

Wu NY, Huang HS, Chao TH, Chou HM, Fang C, Qin CZ, Lin CY, Chu TY, Zhou HH., Cell Rep. 2017 Mar 14;18(11):2557-2565.

                                               

 

  Dr. Wu, Jia-Ru
E-mail:u8931246@yahoo.com.tw
Ext03-8565301#2434(Tzu Chi University)
Tzu Chi University, Taiwan. Ph.D.  

Expertise

 

(Molecular and Cellular Biology)(Cancer Biology)

(Biological Science and Technology)

(Laboratory Medicine and Biotechnology)

(Purification and Isolation of Chinese Herbal Medicine)

(Screening of Active Ingredients of Herbal Medicine)

 

Interest

 (Oncology) (Molecular and Cellular Biology) (Screening and Identification of Active Ingredients of Chinese Herbal Medicine)

 

Publication (in five years)

1.

Jia-Ru Wu, Ren-In You, Chi-Tan Hu, Chuan-Chu Cheng, Rudy Rudy, Wen-Sheng wu (2019, Jun). Hydrogen peroxide inducible clone-5 sustains NADPH oxidase-dependent reactive oxygen species-c-jun N-terminal kinase signaling in hepatocellular carcinoma. Oncogenesis, [Paper #ONCSIS-18-0406R]

2.

Chang HY, Wu JR, Gao WY, Lin HR, Chen PY, Chen CI, Wu MJ, Yen JH (2019, Jan). The Cholesterol-Modulating Effect of Methanol Extract of Pigeon Pea (Cajanus cajan (L.) Millsp.) Leaves on Regulating LDLR and PCSK9 Expression in HepG2 Cells.. Molecules, 24(3), doi: 10.3390/molecules24030493.

3. You RI, Wu WS, Cheng CC, Wu JR, Pan SM, Chen CW, Hu CT (2018, Dec). Involvement of N-glycan in Multiple Receptor Tyrosine Kinases Targeted by Ling-Zhi-8 for Suppressing HCC413 Tumor Progression.. Cancers (Basel), 11(1), doi: 10.3390/cancers11010009.
4.

Hu, C.T., Wu, J.R., Cheng, C.C., Wu, W.S. (2017, May). The Therapeutic Targeting of HGF/c-Met Signaling in Hepatocellular Carcinoma: Alternative Approaches. Cancers (Basel), 9(6).

5.

Jia-Ru Wu, Chi-Tan Hu, Ren-In You, Siou-Mei Pan, Chuan-Chu Cheng, Ming-Che Lee, Chao-Chuan Wu, Yao-Jen Chang, Shu-Chuan Lin, Chang–Shan Chen, Teng-Yi Lin, Wen-Sheng Wu (2015, Aug). Hydrogen peroxide inducible clone-5 mediates reactive oxygen species signaling for hepatocellular carcinoma progression. Oncotarget.

6.

Hu CT, Cheng CC, Wu JR, Pan SM, Wu WS (2015, Jul). PKCε-mediated c-Met endosomal processing directs fluctuant c-Met-JNK-paxillin signaling for tumor progression of HepG2. Cellular Signalling, 27(7), 1544-55.

7. Wu JR, Hu CT, You RI, Ma PL, Pan SM, Lee MC, Wu WS (2015, Jan). Preclinical trials for prevention of tumor progression of hepatocellular carcinoma by LZ-8 targeting c-Met dependent and independent pathways. PLoS One, 10(1), e011449

                                               

 

您目前位置:Home News and Events